Gene Therapy Progress and Prospects: Reprograming gene expression by trans-splicing
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/3302596.pdf
Reference37 articles.
1. Johnson JM et al. Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Science 2003; 302: 2141–2144.
2. Garcia-Blanco MA, Baraniak AP, Lasda EL . Alternative splicing in disease and therapy. Nat Biotechnol 2004; 22: 1–13.
3. Takahara T et al. Delay in synthesis of the 3′ splice site promotes trans-splicing of the preceding 5′ splice site. Mol Cell 2005; 18: 245–251.
4. Flouriot G, Brand H, Seraphin B, Gannon F . Natural trans-spliced mRNAs are generated from the human estrogen receptor-alpha (hER alpha) gene. J Biol Chem 2002; 277: 26244–26251.
5. Finta C, Zaphiropoulos PG . Intergenic mRNA molecules resulting from trans-splicing. J Biol Chem 2002; 277: 5882–5890.
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2. RNA Structure Design Improves Activity and Specificity of trans-Splicing-Triggered Cell Death in a Suicide Gene Therapy Approach;Molecular Therapy - Nucleic Acids;2018-06
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