Alzheimer's Aβ(1–42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells-Reference-Cited by-同舟云学术

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Alzheimer's Aβ(1–42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells

Published:1997-09 Issue:9 Volume:3 Page:1021-1023
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Cook David G.,Forman Mark S.,Sung Jane C.,Leight Susan,Kolson Dennis L.,Iwatsubo Takeshi,Lee Virgina M.-Y.,Doms Robert W.

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm0997-1021.pdf

Reference20 articles.

1. Masters, C.L. et al. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl. Acad. Sci. USA 82, 4245–4249 (1985).

2. Kang, J. et al. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325, 733–736 (1987).

3. Suzuki, N. et al. An increased percentage of long amyloid (5 protein is secreted by familial amyloid β protein precursor (βAPP717) mutants. Science 264, 1336–1340 (1994).

4. Iwatsubo, T. et al. Visualization of Aβ 42 (43) and Aβ 40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ 42 (43). Neuron 13, 45–53 (1994).

5. Golde, T.E., Estus, S., Younkin, L.H., Selkoe, D.J. & Younkin, S.C. Processing of the amyloid protein precursor to potentially amyloidogenic derivatives. Science 255, 728–730 (1992).

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