Author:
Shirazi Muhammad Faizan,Andilla Jordi,Lefaudeux Nicolas,Valdes Claudia,Schwarzhans Florian,Durand Marine,Ntatsis Konstantinos,De Jesus Danilo Andrade,Sanchez Brea Luisa,Gocho Kiyoko,Gautier Josselin,Eckmann-Hansen Christina,Torm Marie Elise Wistrup,Amini Abdullah,Klein Stefan,Van Walsum Theo,Grieve Kate,Paques Michel,Larsen Michael,Loza-Alvarez Pablo,Levecq Xavier,Chateau Nicolas,Pircher Michael
Abstract
AbstractWe present a compact multi-modal and multi-scale retinal imaging instrument with an angiographic functional extension for clinical use. The system integrates scanning laser ophthalmoscopy (SLO), optical coherence tomography (OCT) and OCT angiography (OCTA) imaging modalities and provides multi-scale fields of view. For high resolution, and high lateral resolution in particular, cellular imaging correction of aberrations by adaptive optics (AO) is employed. The entire instrument has a compact design and the scanning head is mounted on motorized translation stages that enable 3D self-alignment with respect to the subject’s eye by tracking the pupil position. Retinal tracking, based on the information provided by SLO, is incorporated in the instrument to compensate for retinal motion during OCT imaging. The imaging capabilities of the multi-modal and multi-scale instrument were tested by imaging healthy volunteers and patients.
Funder
Horizon 2020
Spanish Ministry of Economy and Competitiveness
Fundació Privada Cellex
H2020 Marie Skłodowska-Curie Actions
Laserlab-Europe
Publisher
Springer Science and Business Media LLC
Cited by
13 articles.
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