Loss of PTEN-assisted G2/M checkpoint impedes homologous recombination repair and enhances radio-curability and PARP inhibitor treatment response in prostate cancer-Reference-Cited by-同舟云学术

Loss of PTEN-assisted G2/M checkpoint impedes homologous recombination repair and enhances radio-curability and PARP inhibitor treatment response in prostate cancer

Published:2018-03-02 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Mansour W. Y.,Tennstedt P.,Volquardsen J.,Oing C.,Kluth M.,Hube-Magg C.,Borgmann K.,Simon R.,Petersen C.,Dikomey E.,Rothkamm K.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-22289-7.pdf

Reference37 articles.

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2. Rothkamm, K., Kruger, I., Thompson, L. H. & Lobrich, M. Pathways of DNA double-strand break repair during the mammalian cell cycle. Molecular and cellular biology 23, 5706–5715 (2003).

3. Mansour, W. Y. et al. Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks. Nucleic Acids Res 36, 4088–4098, https://doi.org/10.1093/nar/gkn347 (2008).

4. Bentley, J., Diggle, C. P., Harnden, P., Knowles, M. A. & Kiltie, A. E. DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining. Nucleic Acids Res 32, 5249–5259, https://doi.org/10.1093/nar/gkh842 (2004).

5. Kotter, A. et al. Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells. Mol Oncol 8, 1616–1625, https://doi.org/10.1016/j.molonc.2014.06.008 (2014).

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