Author:
Rybicki Maciej Jan,Becue Ilse,Daeseleire Els,Klimek-Turek Anna,Dzido Tadeusz Henryk
Abstract
AbstractSolvent Front Position Extraction is a novel technique developed for effective sample preparation of biological samples containing coccidiostats prior to LC–MS/MS. In this study the technique was used for isolation and determination of seven coccidiostats, from both main groups being: ionophores and chemical coccidiostats. Its effectiveness was evaluated by comparing with other sample preparation procedures, used in European routine laboratories. Results obtained by Solvent Front Position Extraction were very satisfactory (linearity R2 ≥ 0.971, recovery 90.1–111.1%, RSDr: 8.7–16.6%, RSDR: 9.0–17.7%) and fulfilled requirements described in Commission Regulation (EU) 2021/808 of 22 March 2021, which showed great potential of the technique in sample preparation of coccidiostats in poultry feed.
Funder
Medical University of Lublin, Poland
Publisher
Springer Science and Business Media LLC
Reference38 articles.
1. FDA Annual Summary Report on Antimicrobials Sold or Distributed in 2019 for Use in Food-Producing Animals. https://www.fda.gov/media/144427/download (2020).
2. British Poultry Council Antibiotic Report 2019. https://britishpoultry.org.uk/bpc-antibiotics-report-2019/.
3. Rybicki, M. J. Coccidiostats in treating coccidiosis. ŻYWNOŚĆ. Nauka. Technologia. Jakość, 27, 4(125), 127–137 https://doi.org/10.15193/zntj/2020/125/364 (2020).
4. Roila, R. et al. Occurrence and residue concentration of coccidiostats in feed and food of animal origin; human exposure assessment. Foods 8, 477. https://doi.org/10.3390/foods8100477 (2019).
5. Kennedy, D. G., Cannavan, A. & McCracken, R. J. Regulatory problems caused by contamination, a frequently overlooked cause of veterinary drug residues. J. Chromatogr. A. 882, 37–52 (2000).
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献