Visual field prediction using a deep bidirectional gated recurrent unit network model

Author:

Kim Hwayeong,Lee Jiwoong,Moon Sangwoo,Kim Sangil,Kim Taehyeong,Jin Sang Wook,Kim Jung Lim,Shin Jonghoon,Lee Seung Uk,Jang Geunsoo,Hu Yuanmeng,Park Jeong Rye

Abstract

AbstractAlthough deep learning architecture has been used to process sequential data, only a few studies have explored the usefulness of deep learning algorithms to detect glaucoma progression. Here, we proposed a bidirectional gated recurrent unit (Bi-GRU) algorithm to predict visual field loss. In total, 5413 eyes from 3321 patients were included in the training set, whereas 1272 eyes from 1272 patients were included in the test set. Data from five consecutive visual field examinations were used as input; the sixth visual field examinations were compared with predictions by the Bi-GRU. The performance of Bi-GRU was compared with the performances of conventional linear regression (LR) and long short-term memory (LSTM) algorithms. Overall prediction error was significantly lower for Bi-GRU than for LR and LSTM algorithms. In pointwise prediction, Bi-GRU showed the lowest prediction error among the three models in most test locations. Furthermore, Bi-GRU was the least affected model in terms of worsening reliability indices and glaucoma severity. Accurate prediction of visual field loss using the Bi-GRU algorithm may facilitate decision-making regarding the treatment of patients with glaucoma.

Funder

Busan, Republic of Korea

Ministry of Health & Welfare, Republic of Korea

Korean government

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference39 articles.

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