High-Affinity Functional Fluorescent Ligands for Human β-Adrenoceptors

Author:

Mitronova Gyuzel Y.ORCID,Lukinavičius GražvydasORCID,Butkevich Alexey N.,Kohl Tobias,Belov Vladimir N.ORCID,Lehnart Stephan E.ORCID,Hell Stefan W.ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference50 articles.

1. Ross, E. M., Maguire, M. E., Sturgill, T. W., Biltonen, R. L. & Gilman, A. G. Relationship between Beta-Adrenergic-Receptor and Adenylate-Cyclase - Studies of Ligand-Binding and Enzyme-Activity in Purified Membranes of S49 Lymphoma-Cells. J. Biol. Chem. 252, 5761–5775 (1977).

2. Delean, A., Stadel, J. M. & Lefkowitz, R. J. A Ternary Complex Model Explains the Agonist-Specific Binding-Properties of the Adenylate Cyclase-Coupled Beta-Adrenergic-Receptor. J. Biol. Chem. 255, 7108–7117 (1980).

3. Rossi, A. M. & Taylor, C. W. Analysis of protein-ligand interactions by fluorescence polarization. Nat. Protoc. 6 (2011).

4. Sridharan, R., Zuber, J., Connelly, S. M., Mathew, E. & Dumont, M. E. Fluorescent approaches for understanding interactions of ligands with G protein coupled receptors. Biochim. Biophys. Acta 1838, 15–33 (2014).

5. Daly, C. J. & McGrath, J. C. Fluorescent ligands, antibodies, and proteins for the study of receptors. Pharmacol. Ther. 100, 101–118 (2003).

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