Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-42220-y.pdf
Reference52 articles.
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3. Brosh, R. & Rotter, V. When mutants gain new powers: news from the mutant p53 field. Nat Rev Cancer 9, 701–713 (2009).
4. Kadia T. M. et al. TP53 mutations in newly diagnosed acute myeloid leukemia: Clinicomolecular characteristics, response to therapy, and outcomes. Cancer (2016).
5. Cho, Y., Gorina, S., Jeffrey, P. D. & Pavletich, N. P. Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science 265, 346–355 (1994).
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