Author:
Anderson Michelle A. E.,Leftwich Philip T.,Wilson Ray,Paladino Leonela Z. Carabajal,Basu Sanjay,Rooney Sara,Adelman Zach N.,Alphey Luke
Abstract
AbstractMolecular tools for modulating transgene expression in Aedes aegypti are few. Here we demonstrate that adjustments to the AePUb promoter length can alter expression levels of two reporter proteins in Ae. aegypti cell culture and in mosquitoes. This provides a simple means for increasing or decreasing expression of a gene of interest and easy translation from cells to whole insects.
Funder
Defense Advanced Research Projects Agency
Wellcome Trust
Biotechnology and Biological Sciences Research Council
Publisher
Springer Science and Business Media LLC
Cited by
1 articles.
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