Semi-rational engineering of a thermostable aldo–keto reductase from Thermotoga maritima for synthesis of enantiopure ethyl-2-hydroxy-4-phenylbutyrate (EHPB)-Reference-Cited by-同舟云学术

Semi-rational engineering of a thermostable aldo–keto reductase from Thermotoga maritima for synthesis of enantiopure ethyl-2-hydroxy-4-phenylbutyrate (EHPB)

Published:2017-06-21 Issue:1 Volume:7 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Wang Zhiguo,Zhou Shuo,Zhang Shuangling,Zhang Sa,Zhu Fangmeng,Jin Xiaolu,Chen Zhenming,Xu Xiaoling

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-017-03947-8.pdf

Reference49 articles.

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3. Goldberg, K., Schroer, K., Lütz, S. & Liese, A. Biocatalytic ketone reduction—a powerful tool for the production of chiral alcohols—part I: processes with isolated enzymes. Appl. Microbiol. Biot. 76, 237–248 (2007).

4. Patel, R. N. Biocatalytic synthesis of intermediates for the synthesis of chiral drug substances. Curr. Opin. Biotech. 12, 587–604 (2001).

5. Shimizu, S., Kataoka, M. & Kita, K. Chiral alcohol synthesis with yeast carbonyl reductases. J. Mol. Catal B-Enzym. 5, 321–325 (1998).

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