Engineering the hinge region of human IgG1 Fc-fused bispecific antibodies to improve fragmentation resistance
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-35489-y.pdf
Reference53 articles.
1. Rodgers, K. R. & Chou, R. C. Therapeutic monoclonal antibodies and derivatives: Historical perspectives and future directions. Biotechnol. Adv. 34, 1149–1158 (2016).
2. Chiu, M. L. & Gilliland, G. L. Engineering antibody therapeutics. Curr. Opin. Struct. Biol. 38, 163–173 (2016).
3. Marvin, J. S. & Zhu, Z. P. Recombinant approaches to IgG-like bispecific antibodies. Acta Pharmacol. Sin. 26, 649–658 (2005).
4. Rathi, C. & Meibohm, B. Clinical Pharmacology of Bispecific Antibody Constructs. J. Clin. Pharmacol. 55, S21–S28 (2015).
5. Rath, T. et al. Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics. Crit. Rev. Biotechnol. 35, 235–254 (2015).
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