Lysosomal Targeting Enhancement by Conjugation of Glycopeptides Containing Mannose-6-phosphate Glycans Derived from Glyco-engineered Yeast
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-26913-4.pdf
Reference40 articles.
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2. Oh, D. B. Glyco-engineering strategies for the development of therapeutic enzymes with improved efficacy for the treatment of lysosomal storage diseases. BMB reports 48, 438–444 (2015).
3. Ohashi, T. Enzyme replacement therapy for lysosomal storage diseases. Pediatric endocrinology reviews: PER 10(Suppl 1), 26–34 (2012).
4. Baldo, B. A. Enzymes approved for human therapy: indications, mechanisms and adverse effects. BioDrugs: clinical immunotherapeutics, biopharmaceuticals and gene therapy 29, 31–55, https://doi.org/10.1007/s40259-015-0116-7 (2015).
5. Zhu, Y. et al. Carbohydrate-remodelled acid alpha-glucosidase with higher affinity for the cation-independent mannose 6-phosphate receptor demonstrates improved delivery to muscles of Pompe mice. The Biochemical journal 389, 619–628, https://doi.org/10.1042/BJ20050364 (2005).
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