Early and Pre-Clinical Detection of Prion Seeding Activity in Cerebrospinal Fluid of Goats using Real-Time Quaking-Induced Conversion Assay
Author:
Funder
Division of Intramural Research, National Institute of Allergy and Infectious Diseases
Ministero della Salute
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-42449-7.pdf
Reference50 articles.
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2. Caughey, B., Raymond, G. J. & Bessen, R. A. Strain-dependent differences in beta-sheet conformations of abnormal prion protein. The Journal of Biological Chemistry 273, 32230–32235 (1998).
3. Deleault, N. R., Harris, B. T., Rees, J. R. & Supattapone, S. Formation of native prions from minimal components in vitro. PNA 104, 9741–974 (2007).
4. Kocisko, D. A. et al. Cell-free formation of protease-resistant prion protein. Nature 370, 471–474 (1994).
5. Saborio, G. P., Permanne, B. & Soto, C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 411, 810–813 (2001).
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