Oncogenic G12D mutation alters local conformations and dynamics of K-Ras
Author:
Funder
LUNGevity Foundation
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-48029-z.pdf
Reference66 articles.
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3. Prior, I. A., Lewis, P. D. & Mattos, C. A comprehensive survey of Ras mutations in cancer. Cancer Res 72, 2457–2467, https://doi.org/10.1158/0008-5472.CAN-11-2612 (2012).
4. Pao, W. et al. KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. Plos Med 2, 57–61, https://doi.org/10.1371/journal.pmed.0020017 (2005).
5. Amado, R. G. et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 26, 1626–1634, https://doi.org/10.1200/JCO.2007.14.7116 (2008).
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