Rationalising drug delivery using nanoparticles: a combined simulation and immunology study of GnRH adsorbed to silica nanoparticles
Author:
Funder
Engineering and Physical Sciences Research Council
University of Strathclyde PhD Studentship
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-35143-7.pdf
Reference42 articles.
1. Tsirikis, P. et al. Differential antibody induction to surface textured silica nanoparticle adjuvants. J. Immunol. 194(Supplement), 71.2 (2015).
2. Wang, T. et al. Enhanced mucosal and systemic immune responses obtained by porous silica nanoparticles used as an oral vaccine adjuvant: effect of silica architecture on immunological properties. Internat. J. Pharma. 436, 351–358 (2012).
3. Mody, K. T. et al. Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery. Nanoscale 5, 5167–5179 (2013).
4. Skrastina, D. et al. Silica nanoparticles as the adjuvant for the immunisation of mice using hepatitis B core virus-like particles. PLoS ONE 9, e114006 (2014).
5. Patwardhan, S. V. et al. Chemistry of Aqueous silica Nanoparticle Surfaces and the Mechanism of Selective Peptide Adsorption. J. Am. Chem. Soc. 134, 6244–6256 (2012).
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