Physiologically-based pharmacokinetic/pharmacodynamic modeling of meropenem in critically ill patients
Author:
Funder
Seedling Engineering project of Sichuan Science and Technology Department
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41598-024-64223-0.pdf
Reference44 articles.
1. Huttner, B. et al. 2019 community-acquired pneumonia treatment guidelines: There is a need for a change toward more parsimonious antibiotic use. Am. J. Respir. Crit. Care Med. 201(10), 1315–1316 (2020).
2. Wunderink, R. G. et al. Cefiderocol versus high-dose, extended-infusion meropenem for the treatment of gram-negative nosocomial pneumonia (APEKS-NP): A randomised, double-blind, phase 3, non-inferiority trial. Lancet Infect. Dis. 21(2), 213–225 (2021).
3. Roberts, J. A. et al. Individualised antibiotic dosing for patients who are critically ill: Challenges and potential solutions. Lancet Infect. Dis. 14(6), 498–509 (2014).
4. Roger, C. B. Louart, beta-lactams toxicity in the intensive care unit: An underestimated collateral damage?. Microorganisms 9(7), 1505 (2021).
5. Grimstein, M. et al. Physiologically based pharmacokinetic modeling in regulatory science: An update from the U.S. Food and drug administration’s office of clinical pharmacology. J. Pharm. Sci. 108(1), 21–25 (2019).
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