The 5-formyltetrahydrofolate futile cycle reduces pathway stochasticity in an extended hybrid-stochastic model of folate-mediated one-carbon metabolism
Author:
Funder
U.S. Department of Health & Human Services | U.S. Public Health Service
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-40230-4.pdf
Reference33 articles.
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2. Ducker, G. S. & Rabinowitz, J. D. One-Carbon Metabolism in Health and Disease. Cell metabolism 25, 27–42, https://doi.org/10.1016/j.cmet.2016.08.009 (2017).
3. Beaudin, A. E. & Stover, P. J. Insights into metabolic mechanisms underlying folate-responsive neural tube defects: a minireview. Birth defects research. Part A, Clinical and molecular teratology 85, 274–284, https://doi.org/10.1002/bdra.20553 (2009).
4. Burr, N. E., Hull, M. A. & Subramanian, V. Folic Acid Supplementation May Reduce Colorectal Cancer Risk in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis. Journal of clinical gastroenterology 51, 247–253, https://doi.org/10.1097/MCG.0000000000000498 (2017).
5. Price, A. J. et al. Circulating Folate and Vitamin B12 and Risk of Prostate Cancer: A Collaborative Analysis of Individual Participant Data from Six Cohorts Including 6875 Cases and 8104 Controls. European urology 70, 941–951, https://doi.org/10.1016/j.eururo.2016.03.029 (2016).
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