Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs-Reference-Cited by-同舟云学术

Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs

Published:2018-03-13 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Nasrallah Chady,Rottier Karine,Marcellin Romain,Compan Vincent,Font Joan,Llebaria Amadeu^ORCID,Pin Jean-Philippe^ORCID,Banères Jean-Louis,Lebon Guillaume

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-22729-4.pdf

Reference38 articles.

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3. Kniazeff, J., Prezeau, L., Rondard, P., Pin, J. P. & Goudet, C. Dimers and beyond: The functional puzzles of class C GPCRs. Pharmacol Ther 130, 9–25 (2011).

4. Urwyler, S. Allosteric modulation of family C G-protein-coupled receptors: from molecular insights to therapeutic perspectives. Pharmacol Rev 63, 59–126 (2011).

5. Kniazeff, J. et al. Closed state of both binding domains of homodimeric mGlu receptors is required for full activity. Nat Struct Mol Biol 11, 706–713 (2004).

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