A thin layer of sucrose octasulfate protects the oesophageal mucosal epithelium in reflux oesophagitis

Author:

Hayakawa Takuya,Kawasaki Shizuka,Hirayama Yutaka,Tsutsui Takuya,Sugiyama Eiji,Adachi Kiyo,Kon Ryo,Suematsu MakotoORCID,Sugiura Yuki

Funder

MEXT | Japan Society for the Promotion of Science

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference30 articles.

1. Donnellan, C., Preston, C., Moayyedi, P. & Sharma, N. WITHDRAWN: Medical treatments for the maintenance therapy of reflux oesophagitis and endoscopic negative reflux disease. Cochrane Database Syst. Rev. CD003245 (2017).

2. Elsborg, L., Beck, B. & Stubgaard, M. Effect of sucralfate on gastroesophageal reflux in esophagitis. Hepatogastroenterology 32, 181–184 (1985).

3. Elsborg, L. & Jørgensen, F. Sucralfate versus cimetidine in reflux oesophagitis. A double-blind clinical study. Scand. J. Gastroenterol. 26, 146–150 (1991).

4. Matsuo, Y., Miyoshi, A. & Sekiguchi, T. Dose finding test of SUL (sucralfate solution) in patients with regurgitant esophagitis. Prog. Med. 10, 2515–2533 (1998).

5. Savarino, E. et al. Drugs for improving esophageal mucosa defense: where are we now and where are we going? Ann. Gastroenterol. 30, 585–591 (2017).

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