Author:
Khani Mahmoud E.,Harris Zachery B.,Osman Omar B.,Zhou Juin W.,Chen Andrew,Singer Adam J.,Arbab M. Hassan
Abstract
AbstractWe present an automatic classification strategy for early and accurate assessment of burn injuries using terahertz (THz) time-domain spectroscopic imaging. Burn injuries of different severity grades, representing superficial partial-thickness (SPT), deep partial-thickness (DPT), and full-thickness (FT) wounds, were created by a standardized porcine scald model. THz spectroscopic imaging was performed using our new fiber-coupled Portable HAndheld Spectral Reflection Scanner, incorporating a telecentric beam steering configuration and an f-$$\theta$$
θ
scanning lens. ASynchronous Optical Sampling in a dual-fiber-laser THz spectrometer with 100 MHz repetition rate enabled high-speed spectroscopic measurements. Given twenty-four different samples composed of ten scald and ten contact burns and four healthy samples, supervised machine learning algorithms using THz-TDS spectra achieved areas under the receiver operating characteristic curves of 0.88, 0.93, and 0.93 when differentiating between SPT, DPT, and FT burns, respectively, as determined by independent histological assessments. These results show the potential utility of our new broadband THz PHASR Scanner for early and accurate triage of burn injuries.
Funder
National Institute of General Medical Sciences
Publisher
Springer Science and Business Media LLC
Reference79 articles.
1. Cairns, C., Kang, K. & Santo, L. National Hospital Ambulatory Medical Care Survey: 2018 Emergency Department Summary Tables. https://www.cdc.gov/nchs/data/nhamcs/web_tables/2018-ed-web-tables-508.pdf (2018).
2. Mertens, D. M., Jenkins, M. E. & Warden, G. D. Outpatient burn management. Nurs. Clin. N. Am. 32, 343 (1997).
3. Baxter, C. R. Management of burn wounds. Dermatol. Clin. 11, 709–714 (1993).
4. Hettiaratchy, S. & Papini, R. Initial management of a major burn: II—Assessment and resuscitation. BMJ 329, 101–103 (2004).
5. Papini, R. Management of burn injuries of various depths. BMJ 329, 158–160 (2004).
Cited by
19 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献