Species generalization and differences in Hedgehog pathway regulation of fungiform and circumvallate papilla taste function and somatosensation demonstrated with sonidegib-Reference-Cited by-同舟云学术

Species generalization and differences in Hedgehog pathway regulation of fungiform and circumvallate papilla taste function and somatosensation demonstrated with sonidegib

Published:2018-11-01 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Kumari A.,Yokota Y.^ORCID,Li L.,Bradley R. M.,Mistretta C. M.

Funder

U.S. Department of Health & Human Services | NIH | National Institute on Deafness and Other Communication Disorders

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-34399-3.pdf

Reference48 articles.

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2. Kumari, A. et al. Hedgehog pathway blockade with the cancer drug LDE225 disrupts taste organs and taste sensation. J Neurophysiol 113, 1034–1040, https://doi.org/10.1152/jn.00822.2014 (2015).

3. Kumari, A. et al. Recovery of taste organs and sensory function after severe loss from Hedgehog/Smoothened inhibition with cancer drug sonidegib. Proc Natl Acad Sci USA 114, E10369–E10378, https://doi.org/10.1073/pnas.1712881114 (2017).

4. Lee, R. T. H., Zhao, Z. & Ingham, P. W. Hedgehog signalling. Development 143, 367–372, https://doi.org/10.1242/dev.120154 (2016).

5. Geurts, A. M. & Moreno, C. Zinc-finger nucleases: new strategies to target the rat genome. Clin Sci (Lond) 119, 303–311, https://doi.org/10.1042/CS20100201 (2010).

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