Author:
Washington Peter,Tariq Qandeel,Leblanc Emilie,Chrisman Brianna,Dunlap Kaitlyn,Kline Aaron,Kalantarian Haik,Penev Yordan,Paskov Kelley,Voss Catalin,Stockham Nathaniel,Varma Maya,Husic Arman,Kent Jack,Haber Nick,Winograd Terry,Wall Dennis P.
Abstract
AbstractStandard medical diagnosis of mental health conditions requires licensed experts who are increasingly outnumbered by those at risk, limiting reach. We test the hypothesis that a trustworthy crowd of non-experts can efficiently annotate behavioral features needed for accurate machine learning detection of the common childhood developmental disorder Autism Spectrum Disorder (ASD) for children under 8 years old. We implement a novel process for identifying and certifying a trustworthy distributed workforce for video feature extraction, selecting a workforce of 102 workers from a pool of 1,107. Two previously validated ASD logistic regression classifiers, evaluated against parent-reported diagnoses, were used to assess the accuracy of the trusted crowd’s ratings of unstructured home videos. A representative balanced sample (N = 50 videos) of videos were evaluated with and without face box and pitch shift privacy alterations, with AUROC and AUPRC scores > 0.98. With both privacy-preserving modifications, sensitivity is preserved (96.0%) while maintaining specificity (80.0%) and accuracy (88.0%) at levels comparable to prior classification methods without alterations. We find that machine learning classification from features extracted by a certified nonexpert crowd achieves high performance for ASD detection from natural home videos of the child at risk and maintains high sensitivity when privacy-preserving mechanisms are applied. These results suggest that privacy-safeguarded crowdsourced analysis of short home videos can help enable rapid and mobile machine-learning detection of developmental delays in children.
Funder
Stanford Interdisciplinary Graduate Fellowship
National Science Foundation Fellowship
Thrasher Research Fund
Stanford NLM Clinical Data Science program
National Institutes of Health
The Hartwell Foundation
David and Lucile Packard Foundation Special Projects Grant
Beckman Center for Molecular and Genetic Medicine
Coulter Endowment Translational Research Grant
Berry Fellowship
Spectrum Pilot Program
Stanford’s Precision Health and Integrated Diagnostics Center
Wu Tsai Neurosciences Institute Neuroscience: Translate Program
Stanford’s Institute of Human Centered Artificial Intelligence
Mr. Peter Sullivan
Publisher
Springer Science and Business Media LLC
Reference59 articles.
1. Steinhubl, S. R., Muse, E. D. & Topol, E. J. The emerging field of mobile health. Sci. Transl. Med. 7(283), 283 (2015).
2. Voss, C. et al. Effect of wearable digital intervention for improving socialization in children with autism spectrum disorder: A randomized clinical trial. JAMA Pediatr. 173(5), 446–454 (2019).
3. Washington, P. et al. Superpowerglass: A wearable aid for the at-home therapy of children with autism. Proc. ACM Interact. Mobile Wear Ubiquitous Technol. 1(3), 112 (2017).
4. Daniels, J. et al. Exploratory study examining the at-home feasibility of a wearable tool for social-affective learning in children with autism. NPJ Digital Med. 1(1), 32 (2018).
5. Kalantarian, H. et al. Labeling images with facial emotion and the potential for pediatric healthcare. Artif. Intell. Med. 98, 77–86 (2019).
Cited by
26 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献