Crowdsourced privacy-preserved feature tagging of short home videos for machine learning ASD detection

Author:

Washington Peter,Tariq Qandeel,Leblanc Emilie,Chrisman Brianna,Dunlap Kaitlyn,Kline Aaron,Kalantarian Haik,Penev Yordan,Paskov Kelley,Voss Catalin,Stockham Nathaniel,Varma Maya,Husic Arman,Kent Jack,Haber Nick,Winograd Terry,Wall Dennis P.

Abstract

AbstractStandard medical diagnosis of mental health conditions requires licensed experts who are increasingly outnumbered by those at risk, limiting reach. We test the hypothesis that a trustworthy crowd of non-experts can efficiently annotate behavioral features needed for accurate machine learning detection of the common childhood developmental disorder Autism Spectrum Disorder (ASD) for children under 8 years old. We implement a novel process for identifying and certifying a trustworthy distributed workforce for video feature extraction, selecting a workforce of 102 workers from a pool of 1,107. Two previously validated ASD logistic regression classifiers, evaluated against parent-reported diagnoses, were used to assess the accuracy of the trusted crowd’s ratings of unstructured home videos. A representative balanced sample (N = 50 videos) of videos were evaluated with and without face box and pitch shift privacy alterations, with AUROC and AUPRC scores > 0.98. With both privacy-preserving modifications, sensitivity is preserved (96.0%) while maintaining specificity (80.0%) and accuracy (88.0%) at levels comparable to prior classification methods without alterations. We find that machine learning classification from features extracted by a certified nonexpert crowd achieves high performance for ASD detection from natural home videos of the child at risk and maintains high sensitivity when privacy-preserving mechanisms are applied. These results suggest that privacy-safeguarded crowdsourced analysis of short home videos can help enable rapid and mobile machine-learning detection of developmental delays in children.

Funder

Stanford Interdisciplinary Graduate Fellowship

National Science Foundation Fellowship

Thrasher Research Fund

Stanford NLM Clinical Data Science program

National Institutes of Health

The Hartwell Foundation

David and Lucile Packard Foundation Special Projects Grant

Beckman Center for Molecular and Genetic Medicine

Coulter Endowment Translational Research Grant

Berry Fellowship

Spectrum Pilot Program

Stanford’s Precision Health and Integrated Diagnostics Center

Wu Tsai Neurosciences Institute Neuroscience: Translate Program

Stanford’s Institute of Human Centered Artificial Intelligence

Mr. Peter Sullivan

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

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