Abstract
AbstractThe Yi is one of fifty-six ethnic populations and one of the most ancient ethnic groups in China. The Liangshan Yi Autonomous Prefecture (LYAP) in Sichuan Province has the single largest Yi community in China. To establish a Yi population database in the LYAP of Sichuan in China, a Goldeneye™ DNA Identification System 20A Kit with 19 autosomal STRs (short tandem repeats) was used. As a result, the total discrimination power (TDP) and the cumulative probability of exclusion (CPE) for these STRs in 1016 unrelated individuals were 0.999999999999999999999897 and 0.9999999597, respectively. Totals of 273 alleles for 19 STRs and 8–22 alleles for each locus were found. The allelic frequencies ranged from 0.0005 to 0.5084. The forensic parameter averages of these STRs were as follows: observed heterozygosity (Hobs) of 78.44%, expected heterozygosity (Hexp) of 79.89%, discrimination power (DP) of 92.66%, and probability of exclusion (PE) of 57.68%. Penta E presented the highest levels of Hobs and DP, whereas TPOX showed the lowest Hobs and DP values. Nei’s standard genetic distance matrix among 31 populations found that the nearest genetic distance to the Yi population was the Sichuan Han (0.0056). Altogether, we first reported the forensic parameters and allele frequencies of 19 autosomal STRs of the Yi group in Liangshan. These 19 STR makers could provide highly informative polymorphisms for individual identification, paternity testing and genetic population analyses.
Publisher
Springer Science and Business Media LLC
Reference36 articles.
1. He, G. et al. Genetic polymorphism investigation of the Chinese Yi minority using PowerPlex(R) Y23 STR amplification system. Int. J. Legal Med. 131, 663–666. https://doi.org/10.1007/s00414-017-1537-2 (2017).
2. He, G. et al. Forensic characteristics and phylogenetic analyses of the Chinese Yi population via 19 X-chromosomal STR loci. Int. J. Legal Med. 131, 1243–1246. https://doi.org/10.1007/s00414-017-1563-0 (2017).
3. Zhang, X. et al. Population data for 20 autosomal STR loci in the Yi ethnic minority from Yunnan Province, Southwest China. Forensic Sci. Int. Genet. 28, e43–e44. https://doi.org/10.1016/j.fsigen.2017.02.017 (2017).
4. Li, J. et al. Allele frequencies of 15 autosomal STR loci in the Yi ethnic minority from Yunnan Province in the far southwest of China. Forensic Sci. Int. Genet. 26, e23–e24. https://doi.org/10.1016/j.fsigen.2016.10.013 (2017).
5. Gao, Y., Jin, T. B., Lai, J. H., Zheng, H. B. & Li, S. B. [The genetic polymorphism of 9 short tandem repeat loci in Yi ethnic group of Yunnan in China]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 23, 216–218 (2006).