Author:
Laveriano-Santos Emily P.,Arancibia-Riveros Camila,Parilli-Moser Isabella,Ramírez-Garza Sonia L.,Tresserra-Rimbau Anna,Ruiz-León Ana María,Estruch Ramón,Bodega Patricia,de Miguel Mercedes,de Cos-Gandoy Amaya,Carral Vanesa,Santos-Beneit Gloria,Fernández-Alvira Juan M.,Fernández-Jiménez Rodrigo,Lamuela-Raventós Rosa M.
Abstract
AbstractTo study the relationship between urinary total polyphenol excretion (TPE) in adolescents and ideal cardiovascular (CVH) metrics. 1151 adolescents aged 12.04 (0.46) years participating in the SI! Program for Secondary Schools were selected based on the availability of urine samples and information required to assess CVH metrics. Data on health behaviours (smoking status, body mass index, physical activity, and healthy diet) and health factors (blood pressure, total cholesterol, and blood glucose) were used to calculate the CVH metrics. TPE in urine was analysed by a Folin-Ciocalteu method after solid-phase extraction. Associations between TPE (categorized into tertiles) and CVH metrics (total and separate scores) were assessed using multilevel mixed-effect regression models. Higher TPE levels were associated with higher (healthier) CVH scores and ideal smoking status (OR 1.54, 95% CI 1.10; 1.87, p value = 0.007), physical activity (OR 1.12, 95% CI 1.02; 1.23, p value = 0.022) and total cholesterol (OR 1.78, 95% CI 1.16; 2.73, p value = 0.009) after multivariate adjustment. An association between TPE and total CVH scores was observed only in boys. Girls with higher TPE had higher rates of ideal total cholesterol and blood pressure. According to our findings, higher urinary TPE is related to better CVH scores, with relevant differences in this association by gender.
Funder
Direcció General de Recerca, Generalitat de Catalunya
Serra Húnter Fellowship
Fondo de Investigación Sanitaria- Instituto de Salud Carlos III
Centro Nacional de Investigaciones Cardiovasculares is supported by the ISCIII, the Ministerio de Ciencia e Innovación, and the Pro CNIC Foundation
Severo Ochoa Center of Excellence
Publisher
Springer Science and Business Media LLC
Cited by
3 articles.
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