A computational study of Anthracyclines interacting with lipid bilayers: Correlation of membrane insertion rates, orientation effects and localisation with cytotoxicity

Author:

Toroz D.,Gould I. R.ORCID

Funder

European Commission

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference43 articles.

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2. Hait, W. N. & Aftab, D. T. Rational design and preclinical pharmacology of drugs for reversing mutidrug resistance. Biochem. Pharmacol. 43, 103–107 (1992).

3. Arcamone, F. Properties of antitumor anthracyclines and new developments in their application; Cain Memorial Award Lecture. Cancer Res. 45, 5995–5999 (1985).

4. Powis, G. Anthracycline metabolism and free radical formation. In: Powis, G. & Prough, R.A. (eds) Metabolism and action of anti-cancer drugs. Taylor & Francis, London. pp 211–246 (1987).

5. Willingham, M. C., Cornwell, M. M., Cardarelli, C. O., Gottesman, M. M. & Pastan, I. Single cell analysis of daunomycin uptake and efflux in multidrug-resistant and sensitive KB cells: effects of verapamil and other drugs. Cancer Res. 46, 5941–5946 (1986).

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