Author:
Del Fiol Fernando de Sá,Pereira Andrade Isaltino
Abstract
AbstractThe COVID-19 brought a new model of sanitary behavior (social distancing, etc.) that may have reduced the transmissibility of respiratory diseases, reflecting in the number of antibiotic prescriptions. This study evaluated antibiotic prescriptions for children throughout Brazil, between 2014 and 2021. An interrupted time series was conducted to assess variations in antibiotic consumption by the 1–12-year-old children. Joinpoint regression was used to assess the monthly variations. 86 million prescriptions were evaluated. On average, there was a 54% reduction in prescriptions during the pandemic. Amoxicillin showed a reduction of 65%. Joinpoint regression showed that the pandemic altered the prescription growth curve, changing the trend to a 22% drop per month. The new sanitary behavior showed us that it is possible, decreasing the use of antibiotics, to control the children’s respiratory health.
Publisher
Springer Science and Business Media LLC
Reference16 articles.
1. Rezel-Potts, E., L’Esperance, V. & Gulliford, M. C. Antimicrobial stewardship in the UK during the COVID-19 pandemic: a population-based cohort study and interrupted time-series analysis. Br. J. Gen. Pract. J. R. Coll. Gen. Pract. 71, e331–e338 (2021).
2. Glazier, R. H. et al. Shifts in office and virtual primary care during the early COVID-19 pandemic in Ontario Canada. CMAJ Can. Med. Assoc. J. 193, E200-e210 (2021).
3. Blix, H. S., Høye, S. Use of antibiotics during the COVID-19 pandemic. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 141 (2021).
4. Knight, B. D. et al. The impact of COVID-19 on community antibiotic use in Canada: an ecological study. Clin. Microbiol. Infect. Off. Publ. Eur. Soc. Clin. Microbiol. Infect. Dis. 28, 426–432 (2022).
5. Van Boeckel, T. P. et al. Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. Lancet. Infect. Dis 14, 742–750 (2014).