Green synthesis of quinazoline derivatives using a novel recyclable nano-catalyst of magnetic modified graphene oxide supported with copper

Abstract

AbstractA new magnetic nano-catalyst system based on graphene oxide was designed and manufactured (GO@Fe3O4@3-chloropropyltrimethoxysilane@(Z)-N'-(2-hydroxybenzylidene)-4-(pyridin-4-yl)benzohydrazide@Cu(II)), and it was checked and confirmed by various analyzes such as FTIR, XRD, EDX, MAPPING, TGA/DSC, VSM and FESEM. This nano-catalyst was used in the three-component one-pot synthesis of quinazoline derivatives. The products were obtained using this efficient catalyst with high efficiency in short time and solvent-free conditions. Easy separation and acceptable recyclability are other advantages of this new nano-catalyst. Also, the catalyst can be recycled 4 times without a significant change in its efficiency.