Immune adaptor SKAP1 acts a scaffold for Polo-like kinase 1 (PLK1) for the optimal cell cycling of T-cells-Reference-Cited by-同舟云学术

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Immune adaptor SKAP1 acts a scaffold for Polo-like kinase 1 (PLK1) for the optimal cell cycling of T-cells

Published:2019-07-18 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Raab Monika,Strebhardt Klaus,Rudd Christopher E.

Funder

Wellcome Trust

Bundesministerium für Bildung und Forschung

Bundesministerium für Bildung, Wissenschaft und Kultur

Gouvernement du Canada | Canadian Institutes of Health Research

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-45627-9.pdf

Reference65 articles.

1. Strebhardt, K. & Ullrich, A. Targeting polo-like kinase 1 for cancer therapy. Nat Rev Cancer 6, 321–330 (2006).

2. Zitouni, S., Nabais, C., Jana, S. C., Guerrero, A. & Bettencourt-Dias, M. Polo-like kinases: structural variations lead to multiple functions. Nat Rev Mol Cell Biol 15, 433–452 (2014).

3. Lu, L. Y. et al. Polo-like kinase 1 is essential for early embryonic development and tumor suppression. Mol Cell Biol 28, 6870–6876 (2008).

4. Holtrich, U. et al. Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors. Proc Natl Acad Sci USA 91, 1736–1740 (1994).

5. Strebhardt, K. Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy. Nat Rev Drug Discov 9, 643–660 (2010).

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