Author:
Burananayok Suparat,Nachatri Wilaiwan,Choothanorm Pimpilalai,Kusolthammarat Kantarat,Jaruthamsophon Kanoot,Yodsawad Chaninporn,Limsakul Praopim,Charupanit Krit
Abstract
AbstractBlood safety is a critical aspect of healthcare systems worldwide involving rigorous screening, testing, and processing protocols to minimize the risk of transfusion-transmitted infections (TTIs). The present study offers a comprehensive assessment of the prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and syphilis among blood donors in southern Thailand. It explores the consequences of the COVID-19 pandemic on the blood transfusion service, donor characteristics, and the prevalence of TTIs. A retrospective analysis of 65,511 blood donors between 2018 and 2022 was conducted at Songklanagarind Hospital, Thailand. The socio-demographic characteristics of the donors were examined using the Chi-square test to assess the relationship between TTIs serological positivity and donor characteristics. The donors were divided into pre-COVID-19 (2018–2019) and during COVID-19 (2020–2022) groups to evaluate the impacts of COVID-19. The study found that HBV had the highest overall prevalence at 243 per hundred thousand (pht), followed by syphilis (118 pht), HCV (32 pht), and HIV (31 pht) over a five-year period of study. After COVID-19, the prevalence of HBV decreased by 21.8%; HCV decreased by 2.1%; HIV increased by 36.4%; and syphilis increased by 9.2%. The socio-demographic characteristics and TTIs prevalence were significantly altered over time. This study provides insights into blood donor characteristics and TTIs prevalence in southern Thailand, highlighting the understanding of the impact of COVID-19 on the spread of TTIs.
Funder
National Science, Research and Innovation Fund (NSRF) and Prince of Songkla University
Publisher
Springer Science and Business Media LLC
Reference58 articles.
1. World Health Organization. Blood Safety and Availability. WHO Fact Sheet No. 279 (World Health Organization, 2014).
2. World Health Organization. Global health estimates 2019: Deaths by cause, age, sex, by country and by region, 2000–2019 (2020).
3. World Health Organization. Global Progress Report on HIV, Viral Hepatitis and Sexually Transmitted Infections, 2021 (World Health Organization, 2021).
4. World Health Organization. Global Hepatitis Report 2017 (2017).
5. Leroi, C. et al. Prevalence of chronic hepatitis B virus infection in Thailand: A systematic review and meta-analysis. Int. J. Infect. Dis. 51, 36–43 (2016).