Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics
Link
http://www.nature.com/articles/5201753.pdf
Reference23 articles.
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2. Bell GI, Horita S, Karam JH : A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus. Diabetes 1984; 33: 176–183.
3. Cox NJ, Wapelhorst B, Morrison VA et al: Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families. Am J Hum Genet 2001; 69: 820–830.
4. Concannon P, Gogolin-Ewens KJ, Hinds DA et al: A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus. Nat Genet 1998; 19: 292–296.
5. Maraganore DM, de Andrade M, Lesnick TG et al: High-resolution whole-genome association study of Parkinson disease. Am J Hum Genet 2005; 77: 685–693.
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