Novel insights into double-stranded RNA-mediated immunopathology
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine
Link
https://www.nature.com/articles/s41577-023-00940-3.pdf
Reference180 articles.
1. Weber, F., Wagner, V., Rasmussen, S. B., Hartmann, R. & Paludan, S. R. Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses. J. Virol. 80, 5059–5064 (2006).
2. Son, K. N., Liang, Z. & Lipton, H. L. Double-stranded RNA is detected by immunofluorescence analysis in RNA and DNA virus infections, including those by negative-stranded RNA viruses. J. Virol. 89, 9383–9392 (2015).
3. Hur, S. Double-stranded RNA sensors and modulators in innate immunity. Annu. Rev. Immunol. 37, 349–375 (2019).
4. Rice, G. I. et al. Mutations in ADAR1 cause Aicardi–Goutières syndrome associated with a type I interferon signature. Nat. Genet. 44, 1243–1248 (2012). This study provides clinical evidence that the detection of self-dsRNA by the innate immune system may be causal to human immunopathology.
5. Chen, Y. G. & Hur, S. Cellular origins of dsRNA, their recognition and consequences. Nat. Rev. Mol. Cell Biol. 23, 286–301 (2022).
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