Pharmacogenomic analysis of rhIL-11 treatment in the HLA-B27 rat model of inflammatory bowel disease

Author:

Peterson RL,Wang L,Albert L,Marchese E,Erickson J,Wong A,Mounts WM,Hayes L,Bouchard P,Keith J,Dorner AJ

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Genetics,Molecular Medicine

Reference71 articles.

1. Hammer RE, Maika SD, Richardson JA, Tang JP, Taurog JD . Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human beta 2m: an animal model of HLA-B27-associated human disorders Cell 1990 63: 1099–1112

2. Keith Jr JC, Albert L, Sonis ST, Pfeiffer CJ, Schaub RG . IL-11, a pleiotropic cytokine: exciting new effects of IL-11 on gastrointestinal mucosal biology Stem Cells 1994 12: (Suppl 1) 79–90

3. Peterson RL, Wang L, Albert L, Keith Jr JC, Dorner AJ . Molecular effects of recombinant human interleukin-11 in the HLA-B27 rat model of inflammatory bowel disease Lab Invest 1998 78: 1503–1512

4. Schwertschlag US, Trepicchio WL, Dykstra KH, Keith JC, Turner KJ, Dorner AJ . Hematopoietic, immunomodulatory and epithelial effects of interleukin-11 Leukemia 1999 13: 1307–1315

5. Trepicchio WL, Bozza M, Pedneault G, Dorner AJ . Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production J Immunol 1996 157: 3627–3634

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