NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
http://www.nature.com/articles/leu2015234.pdf
Reference60 articles.
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3. Cancer Genome Atlas Research Network. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med 2013; 368: 2059–2074.
4. Naoe T, Kiyoi H . Normal and oncogenic FLT3. Cell Mol Life Sci 2004; 61: 2932–2938.
5. Kiyoi H, Towatari M, Yokota S, Hamaguchi M, Ohno R, Saito H et al. Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product. Leukemia 1998; 12: 1333–1337.
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