IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells-Reference-Cited by-同舟云学术

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IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells

Published:2011-03-04 Issue:5 Volume:25 Page:828-837
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Coscia M,Pantaleoni F,Riganti C,Vitale C,Rigoni M,Peola S,Castella B,Foglietta M,Griggio V,Drandi D,Ladetto M,Bosia A,Boccadoro M,Massaia M

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/leu201112.pdf

Reference48 articles.

1. Ghia P, Chiorazzi N, Stamatopoulos K . Microenvironmental influences in chronic lymphocytic leukemia: the role of antigen stimulation. J Intern Med 2008; 264: 549–562.

2. Damle RN, Wasil T, Fais F, Ghiotto F, Valetto A, Allen SL et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 1999; 94: 1840–1847.

3. Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK . Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999; 94: 1848–1854.

4. Caligaris-Cappio F, Ghia P . Novel insights in chronic lymphocytic leukemia: are we coming closer to understanding the pathogenesis of the disease? J Clin Oncol 2008; 26: 4497–4503.

5. Lagneaux L, Delforge A, Bron D, De Bruyn C, Stryckmans P . Chronic lymphocytic leukemic B cells but not normal B cells are rescued from apoptosis by contact with normal bone marrow stromal cells. Blood 1998; 91: 2387–2396.

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