Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21-Reference-Cited by-同舟云学术

Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

Published:2005-05-29 Issue:7 Volume:6 Page:680-688
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Minter Lisa M,Turley Danielle M,Das Pritam,Shin Hyun Mu,Joshi Ila,Lawlor Rebecca G,Cho Ok Hyun,Palaga Tanapat,Gottipati Sridevi,Telfer Janice C,Kostura Lisa,Fauq Abdul H,Simpson Katherine,Such Kimberly A,Miele Lucio,Golde Todd E,Miller Stephen D,Osborne Barbara A

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni1209x.pdf

Reference48 articles.

1. Baron, M. An overview of the Notch signaling pathway. Semin. Cell Dev. Biol. 14, 113–119 (2003).

2. De Strooper, B. et al. A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain. Nature 398, 518–522 (1999).

3. Struhl, G. & Adachi, A. Nuclear access and action of notch in vivo . Cell 93, 649–660 (1998).

4. Kopan, R. & Ilagan, M.X. γ-secretase: proteasome of the membrane? Nat. Rev. Mol. Cell Biol. 5, 499–504 (2004).

5. Radtke, F., Wilson, A., Mancini, S.J.C. & MacDonald, R. Notch regulation of lymphocyte development and function. Nat. Immunol. 5, 247–253 (2004).

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