An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation-Reference-Cited by-同舟云学术

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An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation

Published:2011-10-09 Issue:11 Volume:12 Page:1071-1077
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Wilhelm Christoph,Hirota Keiji,Stieglitz Benjamin,Van Snick Jacques,Tolaini Mauro,Lahl Katharina,Sparwasser Tim,Helmby Helena,Stockinger Brigitta

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni.2133.pdf

Reference41 articles.

1. Erpenbeck, V.J. et al. Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes. J. Allergy Clin. Immunol. 111, 1319–1327 (2003).

2. Shimbara, A. et al. IL-9 and its receptor in allergic and nonallergic lung disease: increased expression in asthma. J. Allergy Clin. Immunol. 105, 108–115 (2000).

3. White, B., Leon, F., White, W. & Robbie, G. Two first-in-human, open-label, phase I dose-escalation safety trials of MEDI-528, a monoclonal antibody against interleukin-9, in healthy adult volunteers. Clin. Ther. 31, 728–740 (2009).

4. Temann, U.A., Laouar, Y., Eynon, E.E., Homer, R. & Flavell, R.A. IL9 leads to airway inflammation by inducing IL13 expression in airway epithelial cells. Int. Immunol. 19, 1–10 (2007).

5. Temann, U.A., Geba, G.P., Rankin, J.A. & Flavell, R.A. Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness. J. Exp. Med. 188, 1307–1320 (1998).

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