Herpesvirus saimiri transformation may help disclose inherent functional defects of mucosal T lymphocytes in patients with gastric adenocarcinoma
Author:
Affiliation:
1. Inmunología, Facultad de Medicina, Universidad Complutense; Madrid Spain
2. Servicio de Cirugía General y Aparato Digestivo, Hospital Universitario Príncipe de Asturias; Alcalá de Henares Spain
Funder
FIS
Fondo de Investigaciones Sanitarias
Ministerio de Educación, Cultura y Deporte
Comunidad Autónoma de Madrid
Publisher
Wiley
Subject
Cell Biology,Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1038/sj.icb.7100157/fullpdf
Reference12 articles.
1. Alteration of signal-transducing molecules and phenotypical characteristics in peripheral blood lymphocytes from gastric carcinoma patients;Kim;Pathobiology,1999
2. Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice;Mizoguchi;Science,1992
3. Immunoregulation in cancer-bearing hosts. Down-regulation of gene expression and cytotoxic function in CD8+ T cells;Loeffler;J Immunol,1992
4. Tumor-bearing mice exhibit a progressive increase in tumor antigen-presenting cell function and a reciprocal decrease in tumor antigen-responsive CD4+ T cell activity;Zou;J Immunol,1992
5. Successful in vitro immortalization of human intestinal mucosal lymphocytes with Herpesvirus saimiri;Martin-Villa;Tissue Antigens,1998
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1. Higher prevalence of LAP+ (Latency TGFβ-Associated Peptide) T cells at the tissue level in patients with early gastric cancer;Cellular Immunology;2022-12
2. Defects at the Posttranscriptional Level Account for the Low TCRζ Chain Expression Detected in Gastric Cancer Independently of Caspase-3 Activity;Journal of Immunology Research;2020-11-28
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