Chemoimmunotherapy with GA101 plus chlorambucil in patients with chronic lymphocytic leukemia and comorbidity: results of the CLL11 (BO21004) safety run-in-Reference-Cited by-同舟云学术

Chemoimmunotherapy with GA101 plus chlorambucil in patients with chronic lymphocytic leukemia and comorbidity: results of the CLL11 (BO21004) safety run-in

Published:2012-08-31 Issue:5 Volume:27 Page:1172-1174
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Goede V,Fischer K,Busch R,Jaeger U,Dilhuydy M-S,Wickham N,De Guibert S,Ritgen M,Langerak A W,Bieska G,Engelke A,Humphrey K,Wenger M,Hallek M

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/leu2012252.pdf

Reference15 articles.

1. Hallek M, Fischer K, Fingerle-Rowson G, Fink AM, Busch R, Mayer J et al. Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial. Lancet 2010; 376: 1164–1174.

2. Woyach JA, Ruppert AS, Peterson B, Rai KR, Lin TS, Appelbaum FR et al. Impact of age on outcomes following initial therapy with various chemotherapy and chemoimmunotherapy regimens in patients with chronic lymphocytic leukemia (CLL): results of CALGB Studies. Blood 2011; 118, (abstract 289).

3. Eichhorst BF, Busch R, Stilgenbauer S, Stauch M, Bergmann MA, Ritgen M et al. First-line therapy with fludarabine compared with chlorambucil does not result in a major benefit for elderly patients with advanced chronic lymphocytic leukemia. Blood 2009; 114: 3382–3391.

4. Hillmen P, Gribben JG, Follows GA, Milligan D, Sayala HA, Moreton P et al. Rituximab plus chlorambucil In patients with CD20-positive B-Cell chronic lymphocytic leukemia (CLL): final response analysis of an Open-Label Phase II Study. Blood 2010; 116, (abstract 697).

5. Foa R, Ciolli S, Di Raimondo F, Del Poeta G, Lauria F, Forconi F et al. Rituximab plus chlorambucil as initial treatment for elderly patients with chronic lymphocytic leukemia (CLL): effect of pre-treatment biological characteristics and gene expression patterns on response to treatment. Blood 2011; 118, (abstract 294).

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