Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd2761.pdf
Reference195 articles.
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5. Epstein, A. C. et al. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 107, 43–54 (2001). References 4 and 5 describe the initial identification and characterization of HIF-regulating PHDs.
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