An Icelandic example of the impact of population structure on association studies
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics
Link
http://www.nature.com/articles/ng1492.pdf
Reference30 articles.
1. Freedman, M.L. et al. Assessing the impact of population stratification on genetic association studies. Nat. Genet. 36, 388–393 (2004).
2. Marchini, J., Cardon, L.R., Phillips, M.S. & Donnelly, P. The effects of human population structure on large genetic association studies. Nat. Genet. 36, 512–517 (2004).
3. Ziv, E. & Burchard, E.G. Human population structure and genetic association studies. Pharmacogenomics 4, 431–441 (2003).
4. Ardlie, K.G., Lunetta, K.L. & Seielstad, M. Testing for population subdivision and association in four case-control studies. Am. J. Hum. Genet. 71, 304–311 (2002).
5. Helgason, A., Nicholson, G., Stefansson, K. & Donnelly, P. A reassessment of genetic diversity in Icelanders: strong evidence from multiple loci for relative homogeneity caused by genetic drift. Ann. Hum. Genet. 67, 281–297 (2003).
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