Paired CRISPR screening libraries for studying the function of the non-coding genome at scale
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Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41551-024-01215-5.pdf
Reference5 articles.
1. Nurk, S. et al. The complete sequence of a human genome. Science 376, 44–53 (2022). This paper provides the latest human genome sequence.
2. Pang, B., van Weerd, J. H., Hamoen, F. L. & Snyder, M. P. Identification of non-coding silencer elements and their regulation of gene expression. Nat. Rev. Mol. Cell Biol. 24, 383–395 (2023). This review article highlights the various NCREs, including silencers.
3. Dimitrieva, S. & Bucher, P. UCNEbase—a database of ultraconserved non-coding elements and genomic regulatory blocks. Nucl. Acids Res. 41, D101–D109 (2012). This paper catalogues the ultraconserved non-coding elements.
4. Yip, K. Y. et al. Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors. Genome Biol. 13, R48 (2012). This paper presents the ENCODE-predicted enhancers in K562 cells.
5. Pang, B. & Snyder, M. P. Systematic identification of silencers in human cells. Nat. Genet. 52, 254–263 (2020). This paper reports the identification of NCREs—silencers.
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