Targeted desialylation and cytolysis of tumour cells by fusing a sialidase to a bispecific T-cell engager-Reference-Cited by-同舟云学术

Targeted desialylation and cytolysis of tumour cells by fusing a sialidase to a bispecific T-cell engager

Published:2024-05-01 Issue:5 Volume:8 Page:499-512
ISSN:2157-846X
Container-title:Nature Biomedical Engineering
language:en
Short-container-title:Nat. Biomed. Eng

Author:

Yang Zhuo,Hou Yingqin,Grande Geramie,Cho Jong Hyun,Wang Chao,Shi Yujie,Zak Jaroslav,Wan Yue,Qin Ke,Liu Dongfang^ORCID,Teijaro John R.,Lerner Richard A.,Wu Peng^ORCID

Funder

U.S. Department of Health & Human Services | National Institutes of Health

Cancer Research Institute

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41551-024-01202-w.pdf

Reference49 articles.

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3. Arvedson, T. et al. Targeting solid tumors with bispecific T cell engager immune therapy. Annu. Rev. Cancer Biol. 6, 17–34 (2021).

4. Singh, A., Dees, S. & Grewal, I. S. Overcoming the challenges associated with CD3+ T-cell redirection in cancer. Br. J. Cancer 124, 1037–1048 (2021).

5. Munn, D. H. & Bronte, V. Immune suppressive mechanisms in the tumor microenvironment. Curr. Opin. Immunol. 39, 1–6 (2016).

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