Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc201028.pdf
Reference23 articles.
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3. Edinger AL, Thompson CB . (2004). An activated mTOR mutant supports growth factor-independent, nutrient-dependent cell survival. Oncogene 23: 5654–5663.
4. English D, Cui Y, Siddiqui RA . (1996). Messenger functions of phosphatidic acid. Chem Phys Lipids 80: 117–132.
5. Fang Y, Vilella-Bach M, Bachmann R, Flanigan A, Chen J . (2001). Phosphatidic acid-mediated mitogenic activation of mTOR signaling. Science 294: 1942–1945.
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