Germline testing and genetic counselling in prostate cancer-Reference-Cited by-同舟云学术

Germline testing and genetic counselling in prostate cancer

Published:2022-04-21 Issue:6 Volume:19 Page:331-343
ISSN:1759-4812
Container-title:Nature Reviews Urology
language:en
Short-container-title:Nat Rev Urol

Author:

Russo Jessica,Giri Veda N.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Urology

Link

https://www.nature.com/articles/s41585-022-00580-7.pdf

Reference89 articles.

1. National Cancer Institute. Genetics of Prostate Cancer (PDQ®) – Health Professional Version. NIH https://www.cancer.gov/types/prostate/hp/prostate-genetics-pdq (2022).

2. Giri, V. N. et al. Implementation of germline testing for prostate cancer: Philadelphia Prostate Cancer Consensus Conference 2019. J. Clin. Oncol. 38, 2798–2811 (2020). This paper provides a comprehensive review of genes involved in prostate cancer risk, screening and therapy, along with a genetic evaluation framework for practice.

3. LaDuca, H. et al. A clinical guide to hereditary cancer panel testing: evaluation of gene-specific cancer associations and sensitivity of genetic testing criteria in a cohort of 165,000 high-risk patients. Genet. Med. 22, 407–415 (2020).

4. Cheng, H. H. et al. Germline and somatic mutations in prostate cancer for the clinician. J. Natl Compr. Cancer Netw. 17, 515–521 (2019).

5. de Bono, J. et al. Olaparib for metastatic castration-resistant prostate cancer. N. Engl. J. Med. 382, 2091–2102 (2020). This paper details a phase III randomized trial of the clinical activity of olaparib in men with mCRPC and DNA repair mutations and led to FDA approval for men with mCRPC and DNA repair mutations after progressing on initial lines of therapy.

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