Loss of β-cell mass — an acute event before T1DM presentation?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
http://www.nature.com/articles/nrendo.2017.33.pdf
Reference10 articles.
1. Knip, M. & Simell, O. Environmental triggers of type 1 diabetes. Cold Spring Harb. Perspect. Med. 2, a007690 (2012).
2. Eisenbarth, G. S. Type I diabetes mellitus. A chronic autoimmune disease. N. Engl. J. Med. 314, 1360–1368 (1986).
3. Campbell-Thompson, M. et al. Insulitis and ß-cell mass in the natural history of type 1 diabetes. Diabetes 65, 719–731 (2016).
4. Krogvold, L. et al. Function of isolated pancreatic islets from patients at onset of type 1 diabetes: insulin secretion can be restored after some days in a nondiabetogenic environment in vitro: results from the DiViD study. Diabetes 64, 2506–2512 (2015).
5. Rodriguez-Calvo, T. et al. Increase in pancreatic proinsulin and preservation of beta cell mass in autoantibody positive donors prior to type 1 diabetes onset. Diabetes https://doi.org/10.2337/db16-1343 (2017).
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