Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1-Reference-Cited by-同舟云学术

Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1

Published:2019-05-13 Issue:6 Volume:25 Page:988-1000
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Yousef Hanadie,Czupalla Cathrin J.,Lee Davis,Chen Michelle B.,Burke Ashley N.,Zera Kristy A.,Zandstra Judith,Berber Elisabeth,Lehallier Benoit,Mathur Vidhu,Nair Ramesh V.,Bonanno Liana N.,Yang Andrew C.,Peterson Todd,Hadeiba Husein,Merkel Taylor,Körbelin Jakob,Schwaninger Markus^ORCID,Buckwalter Marion S.^ORCID,Quake Stephen R.,Butcher Eugene C.,Wyss-Coray Tony^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/s41591-019-0440-4.pdf

Reference80 articles.

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2. Harry, G. J. Microglia during development and aging. Pharm. Ther. 139, 313–326 (2013).

3. Mosher, K. I. & Wyss-Coray, T. Microglial dysfunction in brain aging and Alzheimer’s disease. Biochem. Pharmacol. 88, 594–604 (2014).

4. Safaiyan, S. et al. Age-related myelin degradation burdens the clearance function of microglia during aging. Nat. Neurosci. 19, 995–998 (2016).

5. Ming, G. L. & Song, H. Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron 70, 687–702 (2011).

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