T cell lymphoma and secondary primary malignancy risk after commercial CAR T cell therapy

Author:

Ghilardi Guido,Fraietta Joseph A.ORCID,Gerson James N.,Van Deerlin Vivianna M.ORCID,Morrissette Jennifer J. D.,Caponetti Gabriel C.ORCID,Paruzzo Luca,Harris Jaryse C.,Chong Elise A.ORCID,Susanibar Adaniya Sandra P.ORCID,Svoboda Jakub,Nasta Sunita D.,Ugwuanyi Ositadimma H.,Landsburg Daniel J.,Fardella EugenioORCID,Waxman Adam J.,Chong Emeline R.ORCID,Patel Vrutti,Pajarillo Raymone,Kulikovskaya Irina,Lieberman David B.,Cohen Adam D.ORCID,Levine Bruce L.ORCID,Stadtmauer Edward A.,Frey Noelle V.,Vogl Dan T.ORCID,Hexner Elizabeth O.ORCID,Barta Stefan K.,Porter David L.,Garfall Alfred L.,Schuster Stephen J.ORCID,June Carl H.ORCID,Ruella MarcoORCID

Funder

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Laffey-McHugh Foundation

Society for Immunotherapy of Cancer

Leukemia and Lymphoma Society

Publisher

Springer Science and Business Media LLC

Reference48 articles.

1. US FDA. FDA Investigating Serious Risk of T-cell Malignancy Following BCMA-Directed or CD19-Directed Autologous Chimeric Antigen Receptor (CAR) T cell Immunotherapies https://www.fda.gov/vaccines-blood-biologics/safety-availability-biologics/fda-investigating-serious-risk-t-cell-malignancy-following-bcma-directed-or-cd19-directed-autologous (2023).

2. Thomas, A. et al. Second malignancies after multiple myeloma: from 1960s to 2010s. Blood 119, 2731–2737 (2012).

3. Travis, L. B. et al. Second cancers among long-term survivors of non-Hodgkin′s lymphoma. J. Natl Cancer Inst. 85, 1932–1937 (1993).

4. Sacchi, S. et al. Secondary malignancies after treatment for indolent non-Hodgkin′s lymphoma: a 16-year follow-up study. Haematologica 93, 398–404 (2008).

5. Kim, H. N. et al. Composite follicular lymphoma and classic Hodgkin lymphoma. J. Pathol. Transl. Med. 56, 57–60 (2022).

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