Somatostatin regulates brain amyloid β peptide Aβ42 through modulation of proteolytic degradation-Reference-Cited by-同舟云学术

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Somatostatin regulates brain amyloid β peptide Aβ42 through modulation of proteolytic degradation

Published:2005-03-20 Issue:4 Volume:11 Page:434-439
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Saito Takashi,Iwata Nobuhisa,Tsubuki Satoshi,Takaki Yoshie,Takano Jiro,Huang Shu-Ming,Suemoto Takahiro,Higuchi Makoto,Saido Takaomi C

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm1206.pdf

Reference29 articles.

1. Hayashi, M., Yamashita, A. & Shimizu, K. Somatostatin and brain-derived neurotrophic factor mRNA expression in the primate brain: decreased levels of mRNA during aging. Brain Res. 749, 283–289 (1997).

2. Lu, T. et al. Gene regulation and DNA damage in the ageing human brain. Nature 429, 883–891 (2004).

3. Davies, P., Katzman, R. & Terry, R.D. Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer's disease and Alzheimer senile dementia. Nature 288, 279–280 (1980).

4. van de Nes, J.A.P., Sandmann-Keil, D. & Braak, H. Interstitial cells subjacent to the entorhinal region expressing somatostatin-28 immunoreactivity are susceptible to development of Alzheimer's disease–related cytoskeletal changes. Acta Neuropathol. 104, 351–356 (2002).

5. Hardy, J. & Selkoe, D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353–356 (2002).

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