Clinical Relevance of Liver Kinase B1(LKB1) Protein and Gene Expression in Breast Cancer-Reference-Cited by-同舟云学术

Clinical Relevance of Liver Kinase B1(LKB1) Protein and Gene Expression in Breast Cancer

Published:2016-02 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Chen I-Chun,Chang Yuan-Ching,Lu Yen-Shen,Chung Kuei-Pin,Huang Chiun-Sheng,Lu Tzu-Pin,Kuo Wen-Hung,Wang Ming-Yang,Kuo Kuan-Ting,Wu Pei-Fang,Hsueh Tsu-Hsin,Shen Chen-Yang,Lin Ching-Hung,Cheng Ann-Lii

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep21374.pdf

Reference26 articles.

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2. Andrade-Vieira, R., Xu, Z., Colp, P. & Marignani, P. A. Loss of LKB1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathways. PLoS One 8, e56567 (2013).

3. Shackelford, D. B. & Shaw, R. J. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat Rev Cancer 9, 563–575 (2009).

4. Imai, K., Inukai, K., Ikegami, Y., Awata, T. & Katayama, S. LKB1, an upstream AMPK kinase, regulates glucose and lipid metabolism in cultured liver and muscle cells. Biochem Biophys Res Commun 351, 595–601 (2006).

5. Li, J. et al. Loss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion. J Exp Clin Cancer Res 33, 70 (2014).

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