Napyradiomycin A1, an inhibitor of mitochondrial complexes I and II
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology
Link
http://www.nature.com/articles/ja2011138.pdf
Reference18 articles.
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2. Motohashi, K., Sue, M., Furihata, K., Ito, S. & Seto, H. Terpenoids Produced by Actinomycetes: Napyradiomycins from Streptomyces antimycoticus NT17. J. Nat. Prod. 71, 595–601 (2008).
3. Shiomi, K. et al. Novel antibiotics napyradiomycins. Production, isolation, physico-chemical properties and biological activity. J. Antibiot. 39, 487–493 (1986).
4. Pedersen, P L. et al. Preparation and characterization of mitochondria and submitochondrial particles of rat liver and liver-derived tissues. Methods Cell Biol. 20, 411–481 (1978).
5. di Rago, J P. & Colson, A M. Molecular basis for resistance to antimycin and diuron, Q-cycle inhibitors acting at the Qi site in the mitochondrial ubiquinol-cytochrome c reductase in Saccharomyces cerevisiae. J. Biol. Chem. 263, 12564–12570 (1988).
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